The powerful back suffered the injury while being tackled on a 34-yard run in Thursday's preseason opener versus the New England Patriots. Now there's a fresh wound - and a massive one - early in the 2018 season.
The run was negated by a penalty, but it was the first real flash of Guice's talent and potential.
Although initial reports suggested the injury wasn't serious, it appears the severity is much worse than expected. This is a huge blow to a Washington offense that was expecting big things from Guice, the No. 59 overall pick in this year's draft.
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But this was only a "soft" closure - with some deals still able to be completed after this deadline. I think back to back titles is an obsession for them.
Chris Thompson tweeted that he "had a tough time (trying to) hold back the tears" when he learned about the injury.
Instead, Guice's National Football League career starts with a medical redshirt. A year ago at LSU, Guice was hampered by a hyperextended knee, limiting his snaps and forcing him to miss a game.
We know Chris Thompson figures to be a big part of the backfield workforce, but he's also coming off a season-ending injury past year with a fractured right fibula Other candidates include Byron Marshall or Kapri Bibbs, who have some big-play ability. ACL tears typically take at least six months to recover from and the track record of being the same player has been mixed. Kelley averaged 3.13 yards per carry across 62 attempts throughout an injury-plagued 2017 season before being placed on the injured reserve following an abysmal showing against the Minnesota Vikings in Week 10.