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Trainers lift injured San Francisco 49ers quarterback Jimmy Garoppolo (10) who was hurt after a tackle by Kansas City Chiefs defensive back Steven Nelson during the second half of an NFL football game in Kansas City, Mo., Sunday, Sept. 23, 2018.

"It was hard for him last night, it was hard today and it will be hard over these next few weeks", coach Kyle Shanahan said.

Minutes after the news of Garoppolo's injury was confirmed, Matt Maiocco revealed that the 49ers will work out former Houston Texans quarterback Tom Savage.

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Brady, of course, tore his ACL in the very first game of the 2008 season when he was hit in the knee by a Kansas City Chiefs defender. The 49ers signed Garoppolo to a five-year, $137.5 million contract this last offseason.

Coming into this season, Garoppolo was 7-0 in his career between the New England Patriots and the 49ers with 12 touchdowns and five interceptions. He's played in 13 games with nine starts. Beathard, the grandson of Hall of Fame personnel maven Bobby Beathard, went 1-4 as the starter in 2017 after replacing an ineffective Brian Hoyer, completing 54.9 percent of his passes for 4 TDs, 6 INTs and a 64.9 passer rating.