The office of Georgia Secretary of State Brian Kemp, the Republican candidate for governor, said Sunday it had launched an investigation into the Georgia Democratic Party over "a failed attempt to hack the state's voter registration system".
Oprah, 64, gave a rousing speech to Democrat supporters ahead of next Tuesday's vote in which she called Ms Abrams a "changemaker".
Speaking on CNN's "State of the Union "on Sunday, Abrams called the announcement a distraction and political move to sway voters in the final hours of the race". I'm not trying to test any waters - don't want to go in those waters. If Abrams were to win, she would be the first black female governor in American history.
Winfrey explained that in her canvassing, she already talked to people who have voted early and plan on volunteering for Abrams. "I'm not here because I'm making some grandstand because I'm thinking of running myself. I'm not testing the waters", Winfrey said.
Democrats, who have accused Kemp of using Georgia's strict voter identification laws to suppress the vote among minorities, said his office had no basis for opening the probe. But she also said the election is about issues like expanding Medicaid insurance and focusing state spending on public education, job training and small business startups.
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The vice president then joked, "I'm kind of a big deal, too".
The call, sent to an unknown number of Georgians, impersonates Oprah Winfrey, the billionaire media titan who came to Georgia on Thursday to support Abrams.
As a black woman, Winfrey noted her kinship to two groups historically denied ballot access in the United States.
Interesting position, because local Republicans have, from time to time, touting a tax credit that has turned Georgia into a film-making force; the industry contributed an estimated $2.7 billion in direct spending in Georgia previous year, according to a report in the Atlanta Journal Constitution.
On Saturday, it was reported that racist robocalls bankrolled by white supremacists were targeting Abrams and Winfrey.